It's more than likely it will happen. The question is, are you going to let it stop you?
When you step into your power, own who you are without apology, speak your truth - compassionately and kindly, follow your Heart - it is more than likely that people will leave your life. Either quietly, or loudly. The question is - is your Heart pull to your calling, to your Life Purpose, to your destiny louder and stronger, than the people around you, even those you're closest to?
Some people will call you crazy for having such big ideals.
Some people will tell you it's not a good idea (important: don't take advice from those who haven't done what you're doing or thinking about doing, the thing you cannot not do - like you just HAVE to do the thing).
Some people will bitch about you behind your back (which is just them wishing they had the courage to follow their own dreams, like you are).
Some people will give you ultimatums so that you stay in their life. ('If you do that thing, I can't be...